Phenylketonuria+(PKU)



Phenylketonuria is inherited by it being passed down by getting a defective (recessive) gene from both his/hers mom's and dad's genes. EE=Normal Ee=Normal, but the next offspring has a chance of contracting it ee=the child having phenylketonuria.
 * How is it Inherited: **
 * || E || e ||
 * E || EE || Ee ||
 * e || Ee || ee ||

**Signs a nd Sym ptoms:** Phenylketonuria blocks the process that makes phenylalanine takes up the role of making melanin, the pigment for skin color. In other words, tis disorder causes an amino acid, phenylalaline, to build up in your body. Due to PKU, those who have it must follow a strict diet, avoiding foods which contain a large amount of proteins. Because of their lack of protein intake, PKU patients must take daily supplements.
 * Delayed skill socially and mentally
 * Hyperactivity [[image:Screen_shot_2010-08-02_at_9.26.41_PM.png width="272" height="328" align="right"]]
 * Tremors
 * Jerking movements of the arms and legs.
 * Rashes
 * Seizures

PKU is treatable by having a diet very low in phenylalanine, aspartame and protein, taking fish oil and some iron to replace the fatty acids missing from a very strict phenylalanine free diets will help improve the nervous system. The suggested amount of phenylalanine levels in the blood is about two and ten milligrams per deciliter or a metric unit of volume equal to one tenths of a liter. Some foods to avoid when you have phenylketonuria are :
 * Treatments: **
 * Dairy
 * Beans and soybeans
 * Fish [[image:Beef.jpg width="160" height="119" align="right"]]
 * Chocolate [[image:Chicken.jpg width="207" height="154" align="right"]]
 * Pork, chicken and beef
 * Gum
 * Alcoholic substance


 * Interesting Facts: **
 * About one out of 13,500-19,000 people are diagnosed with phenylketonuria.
 * Infants who are diagnosed with PKU appear to be normal in till about a few months old (3 to 5 months of age). The symptoms include being less intensive and having trouble eating. By the age of one, the child is considered mentally retarded.
 * Also called Folling's Disease because Ivar Asbjorn Folling first described it in 1934
 * The life expectancy for untreated females is 69 years of age; untreated males is 79 years of age
 * The chance of having PKU is greater in Ireland and western Scotland
 * In Finland, the incidence happens less than 1 in every 100,000 birth.

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